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DeCS
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Descriptor English:
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DNA-(Apurinic or Apyrimidinic Site) Lyase
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Descriptor Spanish:
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ADN-(sitio apurínico o apirimidínico) liasa
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Descriptor Portuguese:
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DNA Liase (Sítios Apurínicos ou Apirimidínicos)
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Synonyms English:
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AP Endonuclease
AP Lyase
Apurine Apyrimidine Endonuclease
Apurine-Apyrimidine Endonuclease
Apurinic DNA Endonuclease
Apurinic Endonuclease
DNA Endonuclease, Apurinic
DNA Lyase (Apurinic or Apyrimidinic)
Endodeoxyribonuclease (Apurinic or Apyrimidinic)
Endonuclease, AP
Endonuclease, Apurine-Apyrimidine
Endonuclease, Apurinic
Endonuclease, Apurinic DNA
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Tree Number:
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D08.811.074.750
D08.811.520.241.225
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Definition English:
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A DNA repair enzyme that catalyses the excision of ribose residues at apurinic and apyrimidinic DNA sites that can result from the action of DNA GLYCOSYLASES. The enzyme catalyzes a beta-elimination reaction in which the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. This enzyme was previously listed under EC 3.1.25.2. |
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History Note English:
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2004; use DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE (NM) 1980-2003
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Allowable Qualifiers English:
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Record Number:
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38129
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Unique Identifier:
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D043603
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Occurrence in VHL:
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Similar:
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DeCS
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